Original photo by © Mathew Schwartz/Unsplash.com

Pain is a complex topic with a lot of variability. Stepping on a Lego brick with your bare foot feels very different from breaking your leg, though most people would describe both sensations as extremely unpleasant. How we experience pain also varies from person to person. Studies have linked individual pain thresholds to numerous factors, including age, sexual characteristics, and even hair color. But while two people might argue over whether a stomachache or a headache is worse, they’ll likely agree that these spots on the human body are especially sensitive to pain.

Credit: © Ekaterina Demidova—Moment/Getty Images

Fingertips

For a 2014 study on pain sensitivity, University College London (UCL) scientists relied on a concept called “spatial acuity”: the ability to pinpoint the exact source of  a sensation on the body. After using lasers to administer pain to volunteers without activating their touch receptors, the researchers concluded that fingertips are among the body parts most sensitive to pain. This came as a surprise; while anyone who’s had a paper cut knows how sensitive they can be, fingertips actually have a low density of pain-sensing nerve cells compared to other areas. So what explains the findings? According to the scientists’ theory, we  use our fingertips so much that our nervous system adapts them to be extra sensitive.

Credit: © PeopleImages—iStock/Getty Images

Forehead

The same UCL study found that the forehead ranks up there with fingertips as a part of the body that’s especially sensitive to pain. Not only are we keenly aware of discomfort in the face and head, but research shows that we also may have a harder time coping with it. Duke University scientists found that headaches make you extra miserable because your head’s sensory neurons are wired directly into one of your body’s main emotional signaling centers. The difference in suffering between headaches and other types of pain can even be seen on an MRI.

Credit: © Mypointofview/Pexels.com

Cornea

Your skin isn’t the only part of your body that’s densely packed with nerves. Consider the cornea: The transparent layer covering the front of your eye is the most densely innervated tissue in the human body. Scientists estimate that the cornea’s extraordinary density of nociceptors — the nerve cells responsible for detecting pain — makes it 300 to 600 times more sensitive than skin. 

Credit: © triocean—iStock/Getty Images

Shin

While greater nerve density makes it easier to tell where exactly on your body a painful sensation is happening, the level of pain you experience from certain stimuli depends on other factors. One is the level of cushioning that protects the affected area. Your bones are covered in periosteum, a highly sensitive tissue packed with nociceptors. It can get damaged by blunt force trauma when you fall or get hit by something, which causes those painful “bone bruises” you may have experienced. Layers of muscle and fat can help protect the periosteum, but some areas of your body — like the shins — don’t have much of that padding.

Credit: © Rabizo Anatolii/stock.adobe.com 

Funny Bone

Your so-called funny bone, the point on your elbow that can cause brief but startling pain when hit just the wrong way, isn’t a bone at all; it’s actually the ulnar nerve. This nerve extends down the back of your arm to your hand, helping you move your hand and fingers, and at the elbow it runs directly under your skin. That means a bump to your elbow can hit the vulnerable nerve without much tissue to cushion it, leading to a disproportionately sharp shock.

Credit: © CHUBU—E+/Getty Images 

Genitourinary System

No matter your biology, your genitourinary system (the combined urinary and reproductive systems) is likely the part of you that’s most vulnerable to pain. Genitals are densely packed with nerves, as might be expected for organs so important  to the survival of the species. Human testicles are typically on the outside of the body where they’re almost totally unprotected. If they’re hit, the pain can be excruciating, often radiating into the abdomen through a process called “referred pain.” It can be bad enough to cause nausea and vomiting. For people with an ovo-uterine system, pain associated with menstruation (like menstrual cramps) can be so severe that it’s been compared to having a heart attack. Childbirth is also frequently cited as one of the worst pains a human can experience.

However, for many people who’ve experienced it, a certain type of genitourinary pain has no comparison : passing a kidney stone. You might think that the worst part is having a sharp bit of calcified minerals rip through your urethra, but the most painful aspect is typically something called renal colic. This agonizing, cramping flank pain occurs when your urinary system is obstructed. The sensation can radiate through your abdomen and groin, both as a dull ache and sharp waves, and it’s often accompanied by nausea and vomiting. How bad is it? In one study, most women who experienced both said that it was worse than childbirth

So, to avoid the worst pain possible, protect your skin, eyes, bones, and genital area — and, above all, stay hydrated.

Ali Eldridge
Writer

Ali Eldridge is a writer and editor based in Chicago. Currently the editor of "What on Earth! Magazine," she has also contributed extensively to Encyclopaedia Britannica and published several books for children. She spends much of her free time learning new languages and trading puns with her clever kid.

Original photo by slowmotiongli/ iStock

Beneath the adorable exteriors of many wild animals lies a beastly side that’s anything but sweet. The traits that can make an animal seem endearing can also mask a more aggressive nature, one that’s driven by their survival instincts and the protection of their young. When we think of lovable animals, we’re often influenced by their friendly and even cuddly pop culture portrayals — but these can be deceiving. For example, despite their docile depictions in animated films, children’s books, holiday songs, and social media, elephants and hippopotamuses are massive, powerful mammals that are among the most deadly to humans — even more than animals we tend to think of as more dangerous, such as lions.

While it may be intuitive to stay away from animals large enough to crush a car, there are plenty of others whose charming appearances may tempt us closer, unaware of the danger they pose. Here are five adorable animals who are secretly vicious — proving that, when it comes to wildlife encounters, it’s best to err on the safe side and express our affection from a distance.  

Credit: gui00878/ iStock

Red Pandas

Red pandas, with their fox-like faces and bushy tails, are undeniably among the most adorable animals on the planet. These small, racoon-like animals, who live mostly on bamboo in the mountain forests of China, India, and other parts of Asia, can be fiercely territorial and quite aggressive when provoked. When they feel threatened, red pandas take a defensive stance, standing on their hind legs and raising their front legs to make themselves appear larger. If this physical warning goes unheeded, they can further deter enemies by releasing a skunk-like odor from scent glands at the base of their tail or using their sharp claws and teeth to protect themselves. Red pandas are also skilled climbers and will often take to the trees to escape danger — or to launch a surprise attack on an unwitting enemy.

Credit: Freder/ iStock

Dolphins

Dolphins are widely beloved for their intelligence, playful behavior, and seemingly friendly nature; they’re known for gliding lithely alongside boats or performing tricks in marine parks. But beneath their smiley exteriors, dolphins have a dangerous side. In the wild, they have been observed exhibiting aggressive behaviors toward other marine life, and their complex social structures can even lead to violent encounters within their own pods. There are 36 species of marine dolphins around the world, which can reside in both warm and cold waters. Some species, such as the bottlenose dolphin, have a reputation for their ruthless hunting tactics and working together to catch their prey. In the wild and in captivity, dolphins have been known to attack humans, sometimes fatally, by ramming, biting, and even holding their victims under water until they drown. Scientists have attributed dolphin attacks in the wild to the stress of swimming alongside humans, as it can disrupt their normal behavior.

Credit: e.borneoland/ Shutterstock

Slow Lorises

Slow lorises may look like stuffed animals with their shiny, saucer-like eyes, but these small, nocturnal Asian primates aren’t as cuddly as they may first appear. In fact, although they primarily eat tree gum and insects, they are one of only a few venomous mammals. The slow loris has a gland in its upper arm that produces a highly toxic venom, which pools in the grooves of the animal’s razor-sharp canine teeth when licked. Scientists have discovered that one component of this venom is similar to the protein found in cat dander that can trigger allergies in humans. Unlike venomous snakes, which use their bite to immobilize their prey, the slow loris is most likely to bite other slow lorises as a way of settling territorial disputes. Just one bite from a slow loris can cause severe pain, tissue necrosis, anaphylactic shock, and even death in humans.

Credit: BBeale/ iStock

Kangaroos

When you think of kangaroos, you may conjure up images of the warm, maternal Kanga and her playful son Roo from A.A. Milne’s stories about Winnie-the-Pooh. However, these large, social marsupials — particularly the males —  have a surprisingly aggressive side. During mating season, male kangaroos engage in intense physical battles with their rivals to win over females. They not only grapple and punch with their muscular arms, but they also have the ability to balance on their tail, allowing them to deliver powerful kicks — and inflict serious injuries — with their hind legs. Kangaroos, which can grow to 7 feet and weigh up to 200 pounds, are extremely territorial and can become aggressive if they feel cornered or threatened. They have been known to attack and even kill humans if they perceive them as a threat, either in the wild or in areas where they’ve become too accustomed to our presence.

Credit: erniedecker/ iStock

Otters

The internet is chock-full of playful, endearing otters, including countless videos depicting them as docile creatures who float along on their backs and hold hands while they sleep. However, otters are also skilled hunters who can be unexpectedly brutal. The 13 global otter species are uniquely adapted for life both on land and in the water, with dense fur, webbed forelegs, and ears and nostrils that can close airtight when submerged underwater. In the wild, otters are known to hunt and kill fish, birds, and — when they hunt in groups — even mammals larger than themselves. They have sharp teeth and powerful jaws, which they use to catch and kill prey as well as to defend themselves from enemies. Some species, such as the giant river otter (which can grow up to a whopping 6 feet in length), are particularly aggressive and have been known to attack humans who venture too close to their territory. 

Kristina Wright
Writer

Kristina is a coffee-fueled writer living happily ever after with her family in the suburbs of Richmond, Virginia.