The beloved film character Mary Poppins is known for sweetly singing that “a spoonful of sugar makes the medicine go down.” While it works wonders in the movie, the trick didn’t start with the fictitious nanny; healers, doctors, and pharmacists have relied on sugar to help patients choke down unsavory medications for thousands of years. But at one time, the sweet stuff wasn’t just an add-in — it was often the featured ingredient in healing remedies believed to cure all kinds of ailments. Sugar was used to treat sickness and injury as far back as the first century, when Middle Eastern practitioners prescribed it for dehydration, kidney issues, failing eyesight, and more. During the 11th century, English monks noted sugar’s ability to soothe upset stomachs and digestive issues, and by the Middle Ages doctors tried treating bubonic plague with concoctions of hemp, sugar, and more unpleasant ingredients. As recently as the 1700s, pharmacists recommended a glass of lemon juice and sugar water for asthma attacks.
Mary Poppins’ “A Spoonful of Sugar” was inspired by the polio vaccine.
Disney’s 1964 film is known for its song urging sick children to palate bitter medicine, but the ditty takes its inspiration from children’s vaccines. Songwriter Richard Sherman penned the tune after hearing how his son received the oral polio immunization on a sugar cube.
Part of sugar’s allure — and perhaps perceived medicinal benefits — may have been connected to its former rarity. Some historians believe sugarcane originated in Southeast Asia, where farmers may have grown it as early as 8000 BCE, but refining began around 2,500 years ago in India — a process that made sugar shelf-stable and allowed it to spread to other regions. With far to travel, the sweetener was expensive by the time it reached medieval Europe, and for centuries was mostly reserved for the wealthy. But in 1747, German chemist Andreas Sigismund Marggraf discovered a way to produce sugar that didn’t require the sweltering climates in which sugarcane plants grow. Instead, sugar could be harvested in colder regions from the sugar beet, a root vegetable that grows in about three months. Over the next 100 years, sugar beet factories sprang up across Europe and then America, driving down the price of sugar and eventually giving people of all means a chance to savor a little sweetness — with their medicine or otherwise.
Sugar was once considered a spice, not a sweetener.
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Sugar has been found in space.
Granulated, brown, powdered, pearl, cubed — there’s a lot of sugar on Earth. And surprisingly, there’s sugar in space, too. Researchers first discovered evidence of glycolaldehyde, a type of simple sugar, while looking for molecules in space that could support life. Glycolaldehyde is much less complex than cultivated Earth sugars, with only eight atoms compared to cane sugar’s 45. But when it’s found in space, researchers believe the stuff could play an important role in jump-starting life beyond our planet. That’s because glycolaldehyde can combine with a chemical called propenal to make ribose, a component of ribonucleic acid, which is similar to DNA and found in all living things. So far, glycolaldehyde has been found both in the interstellar gas cloud at the Milky Way’s center and in the gases surrounding a young star 400 light-years from Earth.
Nicole Garner Meeker
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Nicole Garner Meeker is a writer and editor based in St. Louis. Her history, nature, and food stories have also appeared at Mental Floss and Better Report.
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Brass fixtures have seen a resurgence in home design in recent years, especially in their natural, unlacquered form. But those warm, timeless decor pieces aren’t just stylish — they also happen to be natural germ fighters, a handy feature for surfaces our hands frequently come into contact with.
Brass is a durable metal known as an alloy, which means it’s made by combining different metals — in this case, copper and zinc. Copper has antimicrobial properties and can disinfect itself over time, and brass can too. This phenomenon is known as the oligodynamic effect; metals with this ability release ions that disrupt and kill bacteria and viruses.
Bacteria can double their population every 20 minutes.
Under ideal conditions, a single bacterium can reproduce about every 20 minutes, and its exponential growth means one cell can turn into millions in just a few hours.
Studies have shown that, within as little as two hours, more than 99% of germs on copper and brass surfaces were gone. Within eight hours, 100% of previously detectable microbes were eliminated. That includes some of even the nastiest germs: MRSA and regular staph, which can cause deadly infections; VRE, a type of antibiotic-resistant bacteria; and E. coli, the foodborne troublemaker that can cause severe stomach illnesses.
We should note that lacquered finishes block this property, so brass doorknobs, handles, or other fixtures must remain in their natural finish for the antimicrobial properties to work. Unlacquered brass is known to tarnish and get discolored, but since it doesn’t contain iron, it won’t rust, and it can easily be polished — a small tradeoff for fewer germs in the home.
The most contagious disease is widely considered to be measles.
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The total bacteria in your body weigh about as much as your brain.
Scientists once thought bacterial cells outnumbered human cells in our bodies by as much as 10:1. More recent estimates suggest the split is closer to even, so the human body contains roughly as many bacterial cells as human cells.
We have roughly 37 trillion cells in our bodies that act as foundations of our tissues, organs, and blood. By comparison, about 38 trillion microbial cells — bacteria, fungi, and viruses — live in and on our bodies. The vast majority of those are concentrated in the gut, where microbial densities are far higher than elsewhere in the body.
A stomach full of bacteria may sound troublesome, but those bacteria actually help break down food, produce essential nutrients, and support the immune system. The bacteria are collectively known as the microbiome, and they add up to weigh roughly 2 to 4 pounds — roughly the same weight range as the average human brain.
Nicole Villeneuve
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Nicole is a writer, thrift store lover, and group-chat meme spammer based in Ontario, Canada.
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Even among those who brush and floss every day, the human mouth isn’t exactly clean. It contains about 700 different kinds of microbes, including bacteria and fungi, some of which are helpful — but not so helpful that you’d ever want to be bitten by another person. Human bites are in fact even more dangerous than other animal bites, as they’re more likely to become infected as a result of that bacteria. Maybe all those zombie movies are onto something.
This oft-repeated statement is little more than a popular misconception, most likely stemming from the fact that dogs lick their own wounds.
Health care providers treat roughly 250,000 human bites each year, around 10% of which result in an infection among children, who are more likely to be bitten than adults (usually by another child). Humans account for only 3% of all bites seen in emergency rooms, however. Dog bites are by far the most common, followed by those of cats, while bites from smaller animals such as mice, rabbits, and hamsters are more rare.
If any creature has put its teeth on you and broken the skin, you’re advised to seek medical treatment regardless of how cute the offending animal was — better safe than sorry.
The animal with the strongest bite is the Nile crocodile.
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Zombie folklore originated in Haiti.
Though we tend to think of them as cinematic creations, zombies predate motion pictures and can be traced back to Haitian folklore, which is itself rooted in African religious practices. According to the mythos, dead people can be brought back to life by voodoo sorcerers known as bokors.
The zombie (originally spelled “zombi”) was first written about in America in an 1838 article called “The Unknown Painter” published by the Alton Telegraph. In it, a person enslaved by the Spanish artist Bartolome Esteban Murillo claimed that a “zombi” made nightly appearances in Murillo’s studio to work on his apprentices’ paintings, a fantastical notion that was dismissed.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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Ravens are smart — really smart. Studies have shown that they can use tools, remember human faces, and even plan for the future. This behavior cuts both ways for humans: Edgar Allan Poe’s favorite birds have demonstrated a tendency to both favor people who show them kindness and hold grudges against those who treat them poorly. These preferences aren’t fleeting, either — they may last for years.
Like all corvids, ravens are referred to as socially monogamous. This means that mated pairs stick together for life. Other birds that do likewise include the bald eagle, black vulture, and whooping cranes.
Raven intelligence is comparable in some cases to that of chimpanzees, which are among the smartest members of the animal kingdom. What’s more, they aren’t the only ones upending the “bird brain” stereotype. Other members of the corvid family — namely crows, jays, and magpies — have displayed exceptional intelligence as well. So the next time you encounter a raven, be sure you get on its good side. You may make a new friend who won’t forget you anytime soon.
English lore has long claimed that the kingdom will fall if ravens ever leave the Tower of London. With that in mind, it’s little surprise that the Ravenmaster has been an official — and important — position at the landmark since the 1960s. The current Ravenmaster, Barney Chandler, succeeded Christopher Skaife, who wrote a well-received memoir about his experiences tending to the clever birds, whose small stature belies the near-mythical status they occupy in England’s collective imagination.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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What’s the most boring day in history — a day where truly nothing important happened? That was the question posed in 2010 to a computer program named True Knowledge. Designed by computer scientist William Tunstall-Pedoe, the program contained 300 million facts, many of them tied to dates. After scouring those facts and comparing them to their respective dates, True Knowledge decided that April 11, 1954, was the most boring day in the 20th century. Belgium held a general election, some sports events happened, a coup in India was possibly planned but not carried out until two days later, and no notable births or deaths occurred — at least as far as the computer program could figure out.
Although the phrase “April showers bring May flowers” seems to crown the month as a pretty soggy time of year, data suggests that the actual wettest month is usually June.
However, scientists may have some other days to suggest when it comes to the most boring day in history ever. The period from around 1.8 billion to 800 million years ago is known to geologists as “the Boring Billion,” because very little happened on Earth in terms of evolution, atmospheric chemistry, or geologic formation. Basically, it’s like the Earth was on pause for a billion years. It wasn’t until the Cambrian explosion some 530 million years ago, when most major animal groups started to appear in the fossil record, that things really started to get exciting. So chin up, April 11, 1954: You weren’t very interesting, but there’s at least a billion years that you easily beat.
According to a 2022 University of Essex study, the most boring job is data analysis.
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Boredom may be good for your brain.
Today, boredom is under threat, with billions of smartphones bringing nearly limitless distraction to us worldwide. But while boredom may be uncomfortable, it can also be good for our brains. These precious moments of downtime give our brains a much-needed chance to rest, consolidate memories, and reflect on lessons learned throughout the day. Studies have shown that those who experience boredom spend more time thinking about their future, and boredom is also known to spur creativity as well as altruism. So the next time you’re feeling a mind-numbing sense of restlessness, don’t reach for your phone. Instead just let your mind wander — who knows what you’ll dream up?
Darren Orf
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Darren Orf lives in Portland, has a cat, and writes about all things science and climate. You can find his previous work at Popular Mechanics, Inverse, Gizmodo, and Paste, among others.
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Researchers estimate that some 300 million people around the world are colorblind, most of them male. On the opposite end of the spectrum are those with an exceedingly rare genetic condition that allows them to see nearly 100 million colors — or 100 times as many as the rest of us. It’s called tetrachromacy, or “super vision,” and it’s the result of having four types of cone cells in the retina rather than the usual three. (Cones help our eyes detect light and are key to color vision.) Because of the way the condition is passed down via the X chromosome, the mutation occurs exclusively in women.
While humans have three cones to detect light and color, dogs have two. They have trouble seeing red and green, but researchers think they can make out shades of blue and yellow.
One tetrachromat describes her ability this way: “If you and I look at a leaf, I may see magenta running around the outside of the leaf or turquoise in certain parts where you would just see dark green. Where the light is making shadows on the walls, I’m seeing violets and lavenders and turquoise. You’re just seeing gray.” In short, tetrachromats see colors within colors, and even the tiniest change in the color balance of a particular hue will be apparent to them. It's estimated that 12% of women have a fourth retina cone, but only a fraction of them experience tetrachromacy. In total, only about 1% of humans have the condition. The rest of us will just have to close our eyes and imagine what it’s like.
The world’s most common favorite color, according to a global survey, is blue.
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There are three types of heterochromia iridis, or different-colored eyes.
Complete heterochromia is when a person’s irises are each a different color — one blue and one green, for instance. Central heterochromia is when there’s an inner ring of color in the iris that’s different from the outer ring (usually in both eyes); the famous 1985 photo of “Afghan Girl” Sharbat Gula in National Geographic is likely an example. Segmental heterochromia is when a single iris has different colors in different parts, often as a patch or a triangle. Most of the time, heterochromia is a mere genetic quirk that doesn’t affect a person’s vision in the slightest. Some people are born with it, while others develop it later in life.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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Everyone with a cat knows that felines love running around at night, especially when their so-called owners are trying to sleep. Despite that, cats aren’t actually nocturnal — they’re crepuscular, meaning they’re most active during dusk and dawn. The reason they prefer twilight has to do with their hunting instincts, as their eyes are well attuned to low-light conditions that allow them to see their prey while remaining hidden themselves. And because they’re descended from desert hunters, dusk and dawn are also favorable due to cooler temperatures. This doesn’t stop them from sleeping all day, of course, but they’re always ready to wake up in an instant — an adaptation that helps keep them safe from predators and alert to opportunities for tiny prey.
While it’s true that cats have a righting reflex that allows them to turn in the air and orient themselves so they land on their feet, it doesn’t always work. When it doesn’t, it’s usually because they didn’t fall from a height that was high enough.
Cats are hardly the only crepuscular creatures. Deer, rabbits, bears, skunks, and possums are among the other mammals you can see out and about as the sun is rising or setting. Birds such as barn owls and common nighthawks can also be crepuscular. Animals you might be surprised to learn are mostly nocturnal include koalas, beavers, and scorpions, among others — and some of them exhibit a level of nighttime activity that could even tire out your cat.
Animals that are active primarily during the day are diurnal.
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Cats’ eyes have a reflective layer that makes them glow in the dark.
It’s called the tapetum lucidum (Latin for “shining layer”) and it works like a small mirror to reflect light, helping cats see in the murk — another evolutionary adaptation that partially explains why your feline is so wired while you’re snoozing. Cat eyes are special in other ways, too. Their pupils grow up to 50% larger in dim light than ours do, allowing them to see more clearly, and they have more light-sensing rods in the back of their eyes. Dogs, cattle, deer, ferrets, and horses have the tapetum lucidum as well, but their eyes don’t all glow the same color. The hue has to do with the amount of pigment in their retina, as well as other substances in the tapetum, meaning that even two dogs of the same species might have eyes that reflect a different color.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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A howling wind can make it seem as though the air itself is roaring across the landscape. But what we hear on a gusty day isn’t the moving air itself — it’s the way that air interacts with the environment. And the different sounds we associate with wind depend on exactly what the air encounters along the way.
Sound is produced when vibrations travel through a medium such as air to reach our ears. Wind, by itself, is simply air that flows from areas of higher pressure to lower pressure. Smooth air moving uniformly doesn’t vibrate in a way that produces sound waves our ears can detect, so in perfectly unobstructed conditions, the wind could move past you without making any audible noise at all.
Chicago is the windiest city in the United States.
Despite its nickname, Chicago isn’t the country’s windiest city. (In fact, it doesn’t even crack the top 10.) That distinction goes to Cheyenne, Wyoming.
The familiar sounds we associate with wind come from friction. As moving air collides with buildings, rustles leaves, squeezes through cracks, or rushes past uneven surfaces, it creates tiny pressure changes and vibrations. Those disturbances generate sound waves, which is why wind can whistle through a narrow opening or roar through a forest canopy. The faster and more chaotic the airflow becomes, the louder those interactions tend to be.
That’s also why different environments give wind different “voices.” A city full of buildings produces whistles and echoes, forests produce rustling and rushing sounds, and open plains may seem almost silent even when the air is moving quickly.
The scientific term for the whistling sound produced when air flows past an object is Aeolian tone.
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The idiom “tilting at windmills” comes from "Don Quixote."
In one memorable episode of the 1604 novel by Spanish author Miguel de Cervantes, the title character mistakes windmills for fearsome giants and charges at them with his lance. Today the phrase “tilting at windmills” means battling imaginary enemies or pursuing an unrealistic goal. The novel also birthed the term “quixotic,” which refers to someone who is foolishly idealistic and impractical.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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You inherit half of your DNA from each parent, 17% to 34% of which comes from each grandparent for an average of 25%, and 12.5% from each great-grandparent. Beyond that, it gets murky — so much so that you aren’t genetically related to all your ancestors.
The farther up the family tree you go, the more diluted your genetic link becomes; once you get past your great-great-great-grandparents, with whom you share about 3% of your DNA, the more likely it becomes that you aren’t genetically related to your relatives. For example, the percentage drops to a meager 1.56% with your fourth great-grandparents. If you ever see a picture of your great-great-great-great aunt and can’t detect a family resemblance, it may very well be because you didn’t actually inherit any of her DNA.
You inherit more genes from your mother than your father.
Mitochondrial DNA comes from the egg, not the sperm, resulting in you inheriting slightly more genetic material from your mother than you do from your father.
The chance becomes greater with each generation you go back, of course. It increases from a 17.76% chance of not sharing any DNA with one of your sixth great-grandparents to a 37.43% chance with your seventh great-grandparents and a 57.53% chance with your eighth great-grandparents. The DNA you share with most of your cousins is also fairly meager: an average of 14.4% with first cousins, 3.4% with second cousins, and just 0.8% with third cousins.
Your mother’s cousin’s child is your second cousin.
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There are more than four DNA bases.
You may be familiar with the four main DNA bases, but there’s more to our genes than ATGC, aka adenine, thymine, guanine, and cytosine. (Fun fact: The sci-fi movie Gattaca got its name by artfully combining those four letters.)
At least 17 modified DNA letters (aka bases) have been found to date, including 5-formylcytosine (5fC), which was discovered in 2011. Technically a transitional form of cytosine that was corrected by repair enzymes, 5fC is an intermediate base that was found by researchers from the University of Cambridge to exist in tissue as a stable structure.
Michael Nordine
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Michael Nordine is a writer and editor living in Denver. A native Angeleno, he has two cats and wishes he had more.
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In the scorching deserts of North America, where summer temperatures regularly exceed 100 degrees Fahrenheit and rainfall is scarce, a small rodent the size of a hamster is thriving — and it’s possible that it’s never taken a sip of water in its life. The kangaroo rat, named for the powerful hind legs that allow it to bound across the arid desert landscape, has solved one of survival’s trickiest problems: how to live in an environment that provides almost no water at all.
This seemingly miraculous feat is achieved through various evolutional adaptations. One of the kangaroo rat’s key characteristics is its ability to get all the moisture it needs from its primarily seed-based diet. When it breaks down those seeds during digestion, one of the byproducts is a small amount of water — just enough to sustain the animal.
The world’s largest rodent can weigh as much as an NFL wide receiver.
The greater capybara, native to Central and South America, weighs between 110 and 132 pounds on average, but one female specimen in Brazil reached a whopping 201 pounds — roughly the weight of the average male wide receiver.
But producing small amounts of metabolic water alone isn’t enough; kangaroo rats have also developed clever adaptations for conserving water. They don’t sweat or pant like other animals, preventing the loss of much-needed liquid from their bodies, and their kidneys concentrate their urine to an almost crystal-like consistency, with very little water lost through waste. Even their exhaled breath is partially recycled thanks to specialized nasal cavities, which condense moisture to be reabsorbed rather than escaping the body through breathing.
The small, mostly nocturnal rodents also escape much of the daytime heat by remaining in their underground burrows out of the scorching sun. The combination of all these evolutionary and behavioral adaptations allows kangaroo rats — which have a lifespan of between two and six years — to survive in some of Earth’s hottest and harshest environments without drinking a drop of water.
The term for an intense fear of mice and rats is musophobia.
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Camel humps don’t store water.
This common misconception comes from the camel’s ability to go weeks at a time without needing a drink, which is often mistakenly attributed to their supposedly water-storing humps. But those humps — one or two, depending on the species — store fatty tissue, not water.
Food sources are often scarce for camels, so to avoid starvation, they’re able to metabolize the fat in their humps for nutrition. When you see a camel with a deflated or drooping hump, it means the animal has gone quite a long time without food — but the hump will sit upright once the camel has refueled.
Humps aside, camels are excellent at conserving water and surviving in extreme heat. They can lose up to 30% of their body weight due to water loss without suffering fatal consequences — by comparison, other mammals may die at a 12% loss. They also rarely sweat and are capable of drinking huge amounts of water — up to 30 gallons — in one go.
Tony Dunnell
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Tony is an English writer of nonfiction and fiction living on the edge of the Amazon jungle.
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